Whole Lotta Shakin’

IM Kulić, AEX Brown, collaborators, and PC Nelson

Evidence for correlated motion of distant cargos.

Simultaneously imaging both microtubule bundles, and their cellular cargos, showed that microtubule sliding is an important part of cellular transport.

Left: Two color fluorescence image of a Drosophila S2 cell with microtubules shown in red and peroxisomes in green. Right: individual frames showing motions.

IM Kulic and PC Nelson, Europhys Lett  2007; IM Kulić, AEX Brown, H Kim, C Kural, B Blehm, PR Selvin, PC Nelson and VI Gelfand, The role of microtubule movement in bidirectional organelle transport. PNAS 2008.